Adiabatically prepared spin-lock approach for T1ρ-based dynamic glucose enhanced MRI at ultrahigh fields
Chemical exchange sensitive spin-lock and related techniques allow to observe the uptake of administered D-glucose in vivo. The exchange-weighting increases with the magnetic field strength, but inhomogeneities in the radiofrequency (RF) field at ultrahigh field whole-body scanners lead to artifacts...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
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| In: |
Magnetic resonance in medicine
Year: 2016, Volume: 78, Issue: 1, Pages: 215-225 |
| ISSN: | 1522-2594 |
| DOI: | 10.1002/mrm.26370 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1002/mrm.26370 Verlag, Volltext: http://onlinelibrary.wiley.com/doi/10.1002/mrm.26370/abstract 
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| Author Notes: | Patrick Schuenke, Christina Koehler, Andreas Korzowski, Johannes Windschuh, Peter Bachert, Mark E. Ladd, Sibu Mundiyanapurath, Daniel Paech, Sebastian Bickelhaupt, David Bonekamp, Heinz-Peter Schlemmer, Alexander Radbruch, and Moritz Zaiss |
| Summary: | Chemical exchange sensitive spin-lock and related techniques allow to observe the uptake of administered D-glucose in vivo. The exchange-weighting increases with the magnetic field strength, but inhomogeneities in the radiofrequency (RF) field at ultrahigh field whole-body scanners lead to artifacts in conventional spin-lock experiments. Thus, our aim was the development of an adiabatically prepared T1ρ-based imaging sequence applicable to studies of glucose metabolism in tumor patients at ultrahigh field strengths. |
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| Item Description: | Published online: 13 August 2016 Gesehen am 23.06.2017 |
| Physical Description: | Online Resource |
| ISSN: | 1522-2594 |
| DOI: | 10.1002/mrm.26370 |