Expression of the novel hepatitis C virus Core+1/ARF protein in the context of JFH1-based replicons
Hepatitis C virus contains a second open reading frame within the core gene, designated core+1/ARF. Here we demonstrate for the first time expression of core+1/ARF protein in the context of a bicistronic JFH1-based replicon and report the production of two isoforms, core+1/L (long) and core+1/S (sho...
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
18 February 2015
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| In: |
Journal of virology
Year: 2015, Jahrgang: 89, Heft: 9, Pages: 5164-5170 |
| ISSN: | 1098-5514 |
| DOI: | 10.1128/JVI.02351-14 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1128/JVI.02351-14 Verlag, kostenfrei, Volltext: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403472/ 
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| Verfasserangaben: | Ioly Kotta-Loizou, Ioannis Karakasiliotis, Niki Vassilaki, Panagiotis Sakellariou, Ralf Bartenschlager, Penelope Mavromara |
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| 520 | |a Hepatitis C virus contains a second open reading frame within the core gene, designated core+1/ARF. Here we demonstrate for the first time expression of core+1/ARF protein in the context of a bicistronic JFH1-based replicon and report the production of two isoforms, core+1/L (long) and core+1/S (short), with different kinetics. | ||
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