Possible pathogenic mechanism of propofol infusion syndrome Involves coenzyme q
Abstract Background: Propofol is a short-acting intravenous anesthetic agent. In rare conditions, a life-threatening complication known as propofol infusion syndrome can occur. The pathophysiologic mechanism is still unknown. Some studies suggested that propofol acts as uncoupling agent, others sug...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2015
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| In: |
Anesthesiology
Year: 2014, Volume: 122, Issue: 2, Pages: 343-352 |
| ISSN: | 1528-1175 |
| DOI: | 10.1097/ALN.0000000000000484 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1097/ALN.0000000000000484 Verlag, Volltext: http://anesthesiology.pubs.asahq.org/article.aspx?articleid=2091595 
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| Author Notes: | Arnaud Vincent Vanlander, M.D., Juergen Guenther Okun, Ph.D., Annick de Jaeger, M.D., Joél Smet, B.A.Sc., Elien De Latter, B.A.Sc., Boel De Paepe, Ph.D., Georges Dacremont, Ph.D., Birgitte Wuyts, M.D., Ph.D., Bert Vanheel, Ph.D., Peter De Paepe, M.D., Ph.D., Philippe Germaine Jorens, M.D., Ph.D., Niels Van Regenmortel, M.D., Rudy Van Coster, M.D., Ph.D. |
| Summary: | Abstract Background: Propofol is a short-acting intravenous anesthetic agent. In rare conditions, a life-threatening complication known as propofol infusion syndrome can occur. The pathophysiologic mechanism is still unknown. Some studies suggested that propofol acts as uncoupling agent, others suggested that it inhibits complex I or ... |
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| Item Description: | Published online: September 4, 2014 Gesehen am 10.07.2017 |
| Physical Description: | Online Resource |
| ISSN: | 1528-1175 |
| DOI: | 10.1097/ALN.0000000000000484 |