When yeast cells meet, karyogamy!: an example of nuclear migration slowly resolved
Cytoskeleton-mediated transport processes are central to the subcellular organization of cells. The nucleus constitutes the largest organelle of a cell, and studying how it is positioned and moved around during various types of cell morphogenetic processes has puzzled researchers for a long time. No...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2013 May 1
|
| In: |
Nucleus
Year: 2013, Jahrgang: 4, Heft: 3, Pages: 182-188 |
| ISSN: | 1949-1042 |
| Online-Zugang: |
|
| Verfasserangaben: | Romain Gibeaux, and Michael Knop |
| Zusammenfassung: | Cytoskeleton-mediated transport processes are central to the subcellular organization of cells. The nucleus constitutes the largest organelle of a cell, and studying how it is positioned and moved around during various types of cell morphogenetic processes has puzzled researchers for a long time. Now, the molecular architectures of the underlying dynamic processes start to reveal their secrets. In yeast, karyogamy denotes the migration of two nuclei toward each other-termed nuclear congression-upon partner cell mating and the subsequent fusion of these nuclei to form a diploid nucleus. It constitutes a well-studied case. Recent insights completed the picture about the molecular processes involved and provided us with a comprehensive model amenable to quantitative computational simulation of the process. This review discusses our understanding of yeast nuclear congression and karyogamy and seeks to explain how a detailed, quantitative and systemic understanding has emerged from this knowledge. |
|---|---|
| Beschreibung: | Gesehen am 10.08.2017 |
| Beschreibung: | Online Resource |
| ISSN: | 1949-1042 |