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Hierarchical imaging: a new concept for targeted imaging of large volumes from cells to tissues

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Imaging large volumes such as entire cells or small model organisms at nanoscale resolution seemed an unrealistic, rather tedious task so far. Now, technical advances have lead to several electron microscopy (EM) large volume imaging techniques. One is array tomography, where ribbons of ultrathin se...

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Bibliographic Details
Main Authors: Wacker, Irene (Author) , Spomer, Waldemar (Author) , Hofmann, Andreas (Author) , Hillmer, Stefan (Author) , Gengenbach, Ulrich (Author) , Schröder, Rasmus R. (Author)
Format: Article (Journal)
Language:English
Published: 12 December 2016
In: BMC cell biology
Year: 2016, Volume: 17
ISSN:1471-2121
DOI:10.1186/s12860-016-0122-8
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s12860-016-0122-8
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12860-016-0122-8
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Author Notes:Irene Wacker, Waldemar Spomer, Andreas Hofmann, Marlene Thaler, Stefan Hillmer, Ulrich Gengenbach, Rasmus R. Schröder
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Summary:Imaging large volumes such as entire cells or small model organisms at nanoscale resolution seemed an unrealistic, rather tedious task so far. Now, technical advances have lead to several electron microscopy (EM) large volume imaging techniques. One is array tomography, where ribbons of ultrathin serial sections are deposited on solid substrates like silicon wafers or glass coverslips.
Item Description:Gesehen am 15.08.2017
Physical Description:Online Resource
ISSN:1471-2121
DOI:10.1186/s12860-016-0122-8

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