Aortic morphometry at endograft position as assessed by 3D image analysis affects risk of type I endoleak formation after TEVAR

PurposeThe purpose of this study was to identify morphologic factors affecting type I endoleak formation and bird-beak configuration after thoracic endovascular aortic repair (TEVAR).MethodsComputed tomography (CT) data of 57 patients (40 males; median age, 66 years) undergoing TEVAR for thoracic ao...

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Main Authors: Kotelis, Drosos (Author) , Brenke, Carolin (Author) , Wörz, Stefan (Author) , Rengier, Fabian (Author) , Rohr, Karl (Author) , Kauczor, Hans-Ulrich (Author) , Böckler, Dittmar (Author) , Tengg-Kobligk, Hendrik von (Author)
Format: Article (Journal)
Language:English
Published: 22 February 2015
In: Langenbeck's archives of surgery
Year: 2015, Volume: 400, Issue: 4, Pages: 523-529
ISSN:1435-2451
DOI:10.1007/s00423-015-1291-1
Online Access:Verlag, Volltext: http://dx.doi.org/10.1007/s00423-015-1291-1
Verlag, Volltext: https://link.springer.com/article/10.1007/s00423-015-1291-1
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Author Notes:Drosos Kotelis, Carolin Brenke, Stefan Wörz, Fabian Rengier, Karl Rohr, Hans-Ulrich Kauczor, Dittmar Böckler, Hendrik von Tengg-Kobligk
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Summary:PurposeThe purpose of this study was to identify morphologic factors affecting type I endoleak formation and bird-beak configuration after thoracic endovascular aortic repair (TEVAR).MethodsComputed tomography (CT) data of 57 patients (40 males; median age, 66 years) undergoing TEVAR for thoracic aortic aneurysm (34 TAA, 19 TAAA) or penetrating aortic ulcer (n = 4) between 2001 and 2010 were retrospectively reviewed. In 28 patients, the Gore TAG® stent-graft was used, followed by the Medtronic Valiant® in 16 cases, the Medtronic Talent® in 8, and the Cook Zenith® in 5 cases. Proximal landing zone (PLZ) was in zone 1 in 13, zone 2 in 13, zone 3 in 23, and zone 4 in 8 patients. In 14 patients (25 %), the procedure was urgent or emergent. In each case, pre- and postoperative CT angiography was analyzed using a dedicated image processing workstation and complimentary in-house developed software based on a 3D cylindrical intensity model to calculate aortic arch angulation and conicity of the landing zones (LZ).ResultsPrimary type Ia endoleak rate was 12 % (7/57) and subsequent re-intervention rate was 86 % (6/7). Left subclavian artery (LSA) coverage (p = 0.036) and conicity of the PLZ (5.9 vs. 2.6 mm; p = 0.016) were significantly associated with an increased type Ia endoleak rate. Bird-beak configuration was observed in 16 patients (28 %) and was associated with a smaller radius of the aortic arch curvature (42 vs. 65 mm; p = 0.049). Type Ia endoleak was not associated with a bird-beak configuration (p = 0.388). Primary type Ib endoleak rate was 7 % (4/57) and subsequent re-intervention rate was 100 %. Conicity of the distal LZ was associated with an increased type Ib endoleak rate (8.3 vs. 2.6 mm; p = 0.038).ConclusionsCT-based 3D aortic morphometry helps to identify risk factors of type I endoleak formation and bird-beak configuration during TEVAR. These factors were LSA coverage and conicity within the landing zones for type I endoleak formation and steep aortic angulation for bird-beak configuration.
Item Description:Gesehen am 17.08.2017
Physical Description:Online Resource
ISSN:1435-2451
DOI:10.1007/s00423-015-1291-1