CT-guided percutaneous spine biopsy in suspected infection or malignancy: a study of 214 patients = CT-gesteuerte perkutane Wirbelsäulenpunktionen bei Verdacht auf Infektion oder Tumor : eine Studie mit 214 Patienten
<p> <b>Purpose:</b> To retrospectively determine the effectiveness and accuracy of CT-guided percutaneous biopsy of malignant and inflammatory bone lesions of the spine and to assess the reliability of pre-biopsy CT and MRI.</p> <p> <b>Materials and Methods:</b...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English German |
| Published: |
December 2016
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| In: |
RöFo
Year: 2016, Volume: 188, Issue: 12, Pages: 1156-1162 |
| ISSN: | 1438-9010 |
| DOI: | 10.1055/s-0042-116233 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1055/s-0042-116233 Verlag, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-116233 
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| Author Notes: | J. Rehm, S. Veith, M. Akbar, H.U. Kauczor, M.A. Weber |
| Summary: | <p> <b>Purpose:</b> To retrospectively determine the effectiveness and accuracy of CT-guided percutaneous biopsy of malignant and inflammatory bone lesions of the spine and to assess the reliability of pre-biopsy CT and MRI.</p> <p> <b>Materials and Methods:</b> 214 patients with lesions of the spine, which were suspicious either for being malignant or inflammatory, underwent CT-guided biopsy for pathological and/or microbiological detection. Biopsy samples were sent for histological examination in 128/214 patients, for microbiological analysis in 17/214 patients and for both analyses in 69/214 patients. Retrospectively, the diagnostic accuracy and sensitivity/specificity of the pre-interventional imaging (CT and MRI) were determined. In addition, the influence of the biopsy on subsequent patient management was assessed.</p> <p> <b>Results:</b> The accuracy was 94.4 % for histopathological analysis and 97.7 % for microbiological analysis. In 25 % of cases the microbiological analysis revealed an underlying pathogen that was not significantly affected by pre-biopsy antibiotic therapy. The sensitivity/specificity of the pre-biopsy cross-sectional imaging concerning suspected malignancy was 69 %/78 %. For suspected infection, the sensitivity/specificity of pre-biopsy imaging was 81 %/44 %. In 52 % of all cases, the biopsy result changed subsequent patient management.</p> <p> <b>Conclusion:</b> Percutaneous CT-guided spine biopsy is a useful and reliable diagnostic procedure to establish a definitive diagnosis but with a relatively low yield of microorganisms in the case of infection.</p> <p> <b>Key Points:</b> </p> <p>• CT-guided spine biopsy is an accurate and reliable procedure in case of infection and tumour.</p> <p>• The results of the CT-guided spine biopsy have a significant influence on the subsequent patient management.</p> <p>• Pathogen recovery-rate in case of infection is moderate but not significantly affected by prebiopsy antibiotic therapy.</p> <p> <b>Citation Format:</b> </p> <p>• Rehm J, Veith S, Akbar M et al. CT-Guided Percutaneous Spine Biopsy in Suspected Infection or Malignancy: A Study of 214 Patients. Fortschr Röntgenstr 2016; 188: 1156 - 1162</p> |
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| Item Description: | Gesehen am 17.08.2017 |
| Physical Description: | Online Resource |
| ISSN: | 1438-9010 |
| DOI: | 10.1055/s-0042-116233 |