COMPULS: design of a multicenter phenotypic, cognitive, genetic, and magnetic resonance imaging study in children with compulsive syndromes
Compulsivity, the closely linked trait impulsivity and addictive behaviour are associated with several neurodevelopmental disorders, including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive compulsive disorder (OCD). All three disorders show impaired f...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
26 October 2016
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| In: |
BMC psychiatry
Year: 2016, Volume: 16 |
| ISSN: | 1471-244X |
| DOI: | 10.1186/s12888-016-1072-6 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s12888-016-1072-6 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12888-016-1072-6 
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| Author Notes: | Jilly Naaijen, Saskia de Ruiter, Marcel P. Zwiers, Jeffrey C. Glennon, Sarah Durston, David J. Lythgoe, Steven C.R. Williams, Tobias Banaschewski, Daniel Brandeis, Barbara Franke, Jan K. Buitelaar |
| Summary: | Compulsivity, the closely linked trait impulsivity and addictive behaviour are associated with several neurodevelopmental disorders, including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive compulsive disorder (OCD). All three disorders show impaired fronto-striatal functioning, which may be related to altered glutamatergic signalling. Genetic factors are also thought to play an important role in the aetiology of compulsivity-related disorders. |
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| Item Description: | Gesehen am 03.11.2017 |
| Physical Description: | Online Resource |
| ISSN: | 1471-244X |
| DOI: | 10.1186/s12888-016-1072-6 |