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Acdk1 gradient guides surface contraction waves in oocytes

<p>Surface contraction waves (SCWs) are prominent shape changes coupled to cell cycle transitions in oocytes. Here the authors show that SCWs are patterned by the spatiotemporal integration of two conserved modules, cdk1-cyclinB for cell cycle regulation and RhoA/Rok/NMYII for actomyosin contr...

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Bibliographic Details
Main Authors: Bischof, Johanna (Author) , Brand, Christoph A. (Author) , Schwarz, Ulrich S. (Author)
Format: Article (Journal)
Language:English
Published: 11 October 2017
In: Nature Communications
Year: 2017, Volume: 8
ISSN:2041-1723
DOI:10.1038/s41467-017-00979-6
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1038/s41467-017-00979-6
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41467-017-00979-6
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Author Notes:Johanna Bischof, Christoph A. Brand, Kálmán Somogyi, Imre Májer, Sarah Thome, Masashi Mori, Ulrich S. Schwarz & Péter Lénárt
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Summary:<p>Surface contraction waves (SCWs) are prominent shape changes coupled to cell cycle transitions in oocytes. Here the authors show that SCWs are patterned by the spatiotemporal integration of two conserved modules, cdk1-cyclinB for cell cycle regulation and RhoA/Rok/NMYII for actomyosin contractility.</p>
Item Description:Gesehen am 30.11.2017
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-017-00979-6

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