Community effectiveness of pyriproxyfen as a dengue vector control method: a systematic review

Author summary: There is evidence that pyriproxyfen may effectively reduce the density of immature mosquito stages when applied to identified breeding sites. Various formulations are commercially available, and easy to use without a health threat to the user. However, questions remain regarding its...

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Main Authors: Maoz, Dorit (Author) , Runge-Ranzinger, Silvia (Author) , Horstick, Olaf (Author)
Format: Article (Journal)
Language:English
Published: July 17, 2017
In: PLoS neglected tropical diseases
Year: 2017, Volume: 11, Issue: 7
ISSN:1935-2735
DOI:10.1371/journal.pntd.0005651
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1371/journal.pntd.0005651
Verlag, kostenfrei, Volltext: http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005651
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Author Notes:Dorit Maoz, Tara Ward, Moody Samuel, Pie Müller, Silvia Runge-Ranzinger, Joao Toledo, Ross Boyce, Raman Velayudhan, Olaf Horstick
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Summary:Author summary: There is evidence that pyriproxyfen may effectively reduce the density of immature mosquito stages when applied to identified breeding sites. Various formulations are commercially available, and easy to use without a health threat to the user. However, questions remain regarding its use as a single agent in a community setting. Considering its mode of action, it would not be the product of choice for use in an acute outbreak setting. However, for a sustainable community approach, especially slow-release pyriproxyfen formulations seem promising, because they are the longest lasting choice. The analysis suggests, that combination with a second vector control chemical, preferably an adulticide tackling different stages of mosquito development, increases the efficacy of pyriproxyfen and prolongs the duration of a single application. This systematic literature review clearly shows that there is a need for further studies, preferably utilising cluster-randomised controlled (cRCT) designs, to investigate the community effectiveness of pyriproxyfen and to link entomological outcomes to human dengue transmission.
Item Description:Gesehen am 30.11.2017
Physical Description:Online Resource
ISSN:1935-2735
DOI:10.1371/journal.pntd.0005651