Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice

Disrupted bile secretion leads to liver damage characterized by inflammation, fibrosis, eventually cirrhosis, and hepatocellular cancer. As obstructive cholestasis often progresses insidiously, markers for the diagnosis and staging of the disease are urgently needed. To this end, we compiled a compr...

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Main Authors: Abshagen, Kerstin (Author) , Ebert, Matthias (Author) , Weng, Honglei (Author) , Dooley, Steven (Author)
Format: Article (Journal)
Language:English
Published: 20 November 2015
In: BMC systems biology
Year: 2015, Volume: 9
ISSN:1752-0509
DOI:10.1186/s12918-015-0229-0
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s12918-015-0229-0
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12918-015-0229-0
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Author Notes:Kerstin Abshagen, Matthias König, Andreas Hoppe, Isabell Müller, Matthias Ebert, Honglei Weng, Herrmann-Georg Holzhütter, Ulrich M. Zanger, Johannes Bode, Brigitte Vollmar, Maria Thomas and Steven Dooley
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Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice by Abshagen, Kerstin (Author) , Ebert, Matthias (Author) , Weng, Honglei (Author) , Dooley, Steven (Author) ,

BioMed Central 2016

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