Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice
Disrupted bile secretion leads to liver damage characterized by inflammation, fibrosis, eventually cirrhosis, and hepatocellular cancer. As obstructive cholestasis often progresses insidiously, markers for the diagnosis and staging of the disease are urgently needed. To this end, we compiled a compr...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
20 November 2015
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| In: |
BMC systems biology
Year: 2015, Jahrgang: 9 |
| ISSN: | 1752-0509 |
| DOI: | 10.1186/s12918-015-0229-0 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s12918-015-0229-0 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12918-015-0229-0 |
| Verfasserangaben: | Kerstin Abshagen, Matthias König, Andreas Hoppe, Isabell Müller, Matthias Ebert, Honglei Weng, Herrmann-Georg Holzhütter, Ulrich M. Zanger, Johannes Bode, Brigitte Vollmar, Maria Thomas and Steven Dooley |
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Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice
BioMed Central 2016
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