Antidepressant treatment with venlafaxine and mirtazapine: no effect on serum concentration of Vascular Endothelial Growth Factor (VEGF)
Introduction: Depression, stress and antidepressant treatment have been found to modulate the expression of growth factors. Methods: We studied depressed patients receiving randomized treatment with venlafaxine or mirtazapine for 28 days. Results: There was no significant difference between baseline...
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| Main Author: | |
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| Format: | Article (Journal) Editorial |
| Language: | English |
| Published: |
2015
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| In: |
Pharmacopsychiatry
Year: 2015, Volume: 48, Issue: 07, Pages: 292-293 |
| ISSN: | 1439-0795 |
| DOI: | 10.1055/s-0035-1555849 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1055/s-0035-1555849 Verlag, Volltext: http://www.thieme-connect.de.ezproxy.medma.uni-heidelberg.de/DOI/DOI?10.1055/s-0035-1555849 
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| Author Notes: | M. Deuschle, M. Gilles, B. Scharnholz, K.G. Kahl |
| Summary: | Introduction: Depression, stress and antidepressant treatment have been found to modulate the expression of growth factors. Methods: We studied depressed patients receiving randomized treatment with venlafaxine or mirtazapine for 28 days. Results: There was no significant difference between baseline VEGF concentrations in depressed patients compared to healthy controls. We found no significant effect of antidepressant treatment on serum VEGF. Discussion: In contrast to serum BDNF, VEGF may not be a suitable biomarker for effects of antidepressant treatment with venlafaxine or mirtazapine. |
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| Item Description: | Gesehen am 19.12.2017 |
| Physical Description: | Online Resource |
| ISSN: | 1439-0795 |
| DOI: | 10.1055/s-0035-1555849 |