Antidepressant treatment with venlafaxine and mirtazapine: no effect on serum concentration of Vascular Endothelial Growth Factor (VEGF)

Introduction: Depression, stress and antidepressant treatment have been found to modulate the expression of growth factors. Methods: We studied depressed patients receiving randomized treatment with venlafaxine or mirtazapine for 28 days. Results: There was no significant difference between baseline...

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1. Verfasser: Deuschle, Michael (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: 2015
In: Pharmacopsychiatry
Year: 2015, Jahrgang: 48, Heft: 07, Pages: 292-293
ISSN:1439-0795
DOI:10.1055/s-0035-1555849
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1055/s-0035-1555849
Verlag, Volltext: http://www.thieme-connect.de.ezproxy.medma.uni-heidelberg.de/DOI/DOI?10.1055/s-0035-1555849
Volltext
Verfasserangaben:M. Deuschle, M. Gilles, B. Scharnholz, K.G. Kahl
Beschreibung
Zusammenfassung:Introduction: Depression, stress and antidepressant treatment have been found to modulate the expression of growth factors. Methods: We studied depressed patients receiving randomized treatment with venlafaxine or mirtazapine for 28 days. Results: There was no significant difference between baseline VEGF concentrations in depressed patients compared to healthy controls. We found no significant effect of antidepressant treatment on serum VEGF. Discussion: In contrast to serum BDNF, VEGF may not be a suitable biomarker for effects of antidepressant treatment with venlafaxine or mirtazapine.
Beschreibung:Gesehen am 19.12.2017
Beschreibung:Online Resource
ISSN:1439-0795
DOI:10.1055/s-0035-1555849