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Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting

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Rituximab has broad and increasing application in rheumatic diseases. It is known from lymphoma studies that natural killer (NK) cells can lyse rituximab-coated transformed B cells. However, the role of NK cells in mediating rituximab-induced depletion of non-malignant B cells is unknown. The purpos...

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Main Authors: Merkt, Wolfgang (Author) , Lorenz, Hanns-Martin (Author) , Watzl, Carsten (Author)
Format: Article (Journal)
Language:English
Published: 15 September 2016
In: Arthritis Research & Therapy
Year: 2016, Volume: 18
ISSN:1465-9913
DOI:10.1186/s13075-016-1101-3
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13075-016-1101-3
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13075-016-1101-3
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Author Notes:Wolfgang Merkt, Hanns-Martin Lorenz, Carsten Watzl
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Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting by Merkt, Wolfgang (Author) , Lorenz, Hanns-Martin (Author) , Watzl, Carsten (Author) ,

BioMed Central 2016

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