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Image quality of 3rd generation spiral cranial dual-source CT in combination with an advanced model iterative reconstruction technique: a prospective intra-individual comparison study to standard sequential cranial CT using identical radiation dose

Objectives: To prospectively intra-individually compare image quality of a 3rd generation Dual-Source-CT (DSCT) spiral cranial CT (cCT) to a sequential 4-slice Multi-Slice-CT (MSCT) while maintaining identical intra-individual radiation dose levels. Methods: 35 patients, who had a non-contrast enhan...

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Main Authors: Wenz, Holger (Author) , Maros, Máté E. (Author) , Meyer, Mathias (Author) , Förster, Alex (Author) , Haubenreisser, Holger (Author) , Kurth, Stefan (Author) , Schönberg, Stefan (Author) , Groden, Christoph (Author) , Scharf, Johann (Author) , Henzler, Thomas (Author)
Format: Article (Journal)
Language:English
Published: August 19, 2015
In: PLOS ONE
Year: 2015, Volume: 10, Issue: 8
ISSN:1932-6203
DOI:10.1371/journal.pone.0136054
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1371/journal.pone.0136054
Verlag, kostenfrei, Volltext: http://journals.plos.org.ezproxy.medma.uni-heidelberg.de/plosone/article?id=10.1371/journal.pone.0136054
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Author Notes:Holger Wenz, Máté E. Maros, Mathias Meyer, Alex Förster, Holger Haubenreisser, Stefan Kurth, Stefan O. Schoenberg, Thomas Flohr, Christianne Leidecker, Christoph Groden, Johann Scharf, Thomas Henzler
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Summary:Objectives: To prospectively intra-individually compare image quality of a 3rd generation Dual-Source-CT (DSCT) spiral cranial CT (cCT) to a sequential 4-slice Multi-Slice-CT (MSCT) while maintaining identical intra-individual radiation dose levels. Methods: 35 patients, who had a non-contrast enhanced sequential cCT examination on a 4-slice MDCT within the past 12 months, underwent a spiral cCT scan on a 3rd generation DSCT. CTDIvol identical to initial 4-slice MDCT was applied. Data was reconstructed using filtered backward projection (FBP) and 3rd-generation iterative reconstruction (IR) algorithm at 5 different IR strength levels. Two neuroradiologists independently evaluated subjective image quality using a 4-point Likert-scale and objective image quality was assessed in white matter and nucleus caudatus with signal-to-noise ratios (SNR) being subsequently calculated. Results: Subjective image quality of all spiral cCT datasets was rated significantly higher compared to the 4-slice MDCT sequential acquisitions (p<0.05). Mean SNR was significantly higher in all spiral compared to sequential cCT datasets with mean SNR improvement of 61.65% (p*Bonferroni0.05<0.0024). Subjective image quality improved with increasing IR levels. Conclusion: Combination of 3rd-generation DSCT spiral cCT with an advanced model IR technique significantly improves subjective and objective image quality compared to a standard sequential cCT acquisition acquired at identical dose levels.
Item Description:Gesehen am 21.02.2018
Physical Description:Online Resource
ISSN:1932-6203
DOI:10.1371/journal.pone.0136054

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