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CNDP1 genotype and renal survival in pediatric nephropathies

Background: The risk of developing type II diabetic nephropathy (DN) is lower in patients carrying the CNDP1 Mannheim polymorphism (homozygosity for the five leucine repeat), resulting in decreased activity of the histidine-dipeptide metabolizing enzyme carnosinase. The role of CNDP1 in other nephro...

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Main Authors: Peters, Verena (Author) , Kebbewar, Moustafa (Author) , Janssen, Bart (Author) , Hoffmann, Georg F. (Author) , Schmitt, Claus P. (Author) , Schaefer, Franz (Author) , Wühl, Elke (Author)
Format: Article (Journal)
Language:English
Published: 07.06.2016
In: The journal of pediatric endocrinology and metabolism
Year: 2016, Volume: 29, Issue: 7, Pages: 827-833
ISSN:2191-0251
DOI:10.1515/jpem-2015-0262
Online Access:Verlag, Volltext: http://dx.doi.org/10.1515/jpem-2015-0262
Verlag, Volltext: https://www.degruyterbrill.com/view/j/jpem.2016.29.issue-7/jpem-2015-0262/jpem-2015-0262.xml
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Author Notes:Verena Peters, Moustafa Kebbewar, Bart Janssen, Georg F. Hoffmann, Kristina Möller, Simone Wygoda, Marina Charbit, Ana Fernandes-Teixeira, Nikola Jeck, Johannes Zschocke, Claus Peter Schmitt, Franz Schäfer, Elke Wühl, for the ESCAPE Trial Group
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Summary:Background: The risk of developing type II diabetic nephropathy (DN) is lower in patients carrying the CNDP1 Mannheim polymorphism (homozygosity for the five leucine repeat), resulting in decreased activity of the histidine-dipeptide metabolizing enzyme carnosinase. The role of CNDP1 in other nephropathies is still unknown.
Item Description:Gesehen am 05.03.2018
Physical Description:Online Resource
ISSN:2191-0251
DOI:10.1515/jpem-2015-0262

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