CNDP1 genotype and renal survival in pediatric nephropathies
Background: The risk of developing type II diabetic nephropathy (DN) is lower in patients carrying the CNDP1 Mannheim polymorphism (homozygosity for the five leucine repeat), resulting in decreased activity of the histidine-dipeptide metabolizing enzyme carnosinase. The role of CNDP1 in other nephro...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
07.06.2016
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| In: |
The journal of pediatric endocrinology and metabolism
Year: 2016, Jahrgang: 29, Heft: 7, Pages: 827-833 |
| ISSN: | 2191-0251 |
| DOI: | 10.1515/jpem-2015-0262 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1515/jpem-2015-0262 Verlag, Volltext: https://www.degruyterbrill.com/view/j/jpem.2016.29.issue-7/jpem-2015-0262/jpem-2015-0262.xml 
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| Verfasserangaben: | Verena Peters, Moustafa Kebbewar, Bart Janssen, Georg F. Hoffmann, Kristina Möller, Simone Wygoda, Marina Charbit, Ana Fernandes-Teixeira, Nikola Jeck, Johannes Zschocke, Claus Peter Schmitt, Franz Schäfer, Elke Wühl, for the ESCAPE Trial Group |
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| 520 | |a Background: The risk of developing type II diabetic nephropathy (DN) is lower in patients carrying the CNDP1 Mannheim polymorphism (homozygosity for the five leucine repeat), resulting in decreased activity of the histidine-dipeptide metabolizing enzyme carnosinase. The role of CNDP1 in other nephropathies is still unknown. | ||
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