Prognostic significance of pulsatile tinnitus in cervical artery dissection
Background and purpose: Our aim was to investigate whether pulsatile tinnitus (PT) in cervical artery dissection (CeAD) has prognostic significance. Methods: All CeAD patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) study with documentation of PT were analysed. The...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
1 March 2016
|
| In: |
European journal of neurology
Year: 2016, Volume: 23, Issue: 7, Pages: 1183-1187 |
| ISSN: | 1468-1331 |
| DOI: | 10.1111/ene.13031 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1111/ene.13031 Verlag, Volltext: http://onlinelibrary.wiley.com/doi/10.1111/ene.13031/abstract 
|
| Author Notes: | L. Kellert, M. Kloss, A. Pezzini, S. Debette, D. Leys, V. Caso, V.N. Thijs, A. Bersano, E. Touzé, T. Tatlisumak, C. Traenka, P.A. Lyrer, S.T. Engelter, T.M. Metso and C. Grond-Ginsbach for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) study group |
| Summary: | Background and purpose: Our aim was to investigate whether pulsatile tinnitus (PT) in cervical artery dissection (CeAD) has prognostic significance. Methods: All CeAD patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) study with documentation of PT were analysed. The presence of PT was systematically assessed using a standardized questionnaire. Stroke severity at admission was defined according to the National Institutes of Health Stroke Scale (NIHSS). Excellent outcome after 3 months was defined as a modified Rankin Scale of 0-1. Results: Sixty-three of 778 patients (8.1%) reported PT. PT+ patients presented less often with ischaemic stroke (41.3% vs. 63.9%, P < 0.001), more often with dissection in the internal carotid artery (85.7% vs. 64.2%, P = 0.001), less often with vessel occlusion (19.0% vs. 34.1%, P = 0.017) and more often with excellent outcome at 3 months (92.1% vs. 75.4%, P = 0.002). Logistic regression analysis identified PT as an independent predictor of excellent outcome after 3 months [odds ratio (OR) 3.96, 95% confidence interval (CI) 1.22-12.87] adjusted to significant outcome predictors NIHSS on admission (OR 0.82, 95% CI 0.79-0.86), Horner syndrome (OR 1.95, 95% CI 1.16-3.29) and vessel occlusion (OR 0.62, 95% CI 0.40-0.94) and to non-significant predictors age, sex, pain and location of CeAD. Conclusion: The presence of PT in CeAD is associated with a benign clinical course and predicts a favourable outcome. |
|---|---|
| Item Description: | Gesehen am 09.03.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1468-1331 |
| DOI: | 10.1111/ene.13031 |