Pharmakotherapie des Schmerzes bei älteren Patienten mit Nichtopioiden = Non-opioid pain medication in the elderly

Non-opioid analgesics are frequently used to control chronic pain in elderly patients; however some of these drugs show high rates of adverse drug reactions. Among these are significant clinical problems which impede an effective and safe pain control. This review provides recent data concerning non...

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Hauptverfasser: Burkhardt, Heinrich (VerfasserIn) , Wehling, Martin (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Deutsch
Veröffentlicht: 5. August 2015
In: Der Schmerz
Year: 2015, Jahrgang: 29, Heft: 4, Pages: 371-379
ISSN:1432-2129
DOI:10.1007/s00482-015-0032-2
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1007/s00482-015-0032-2
Verlag, Volltext: https://link-springer-com.ezproxy.medma.uni-heidelberg.de/article/10.1007/s00482-015-0032-2
Volltext
Verfasserangaben:H. Burkhardt, M. Wehling
Beschreibung
Zusammenfassung:Non-opioid analgesics are frequently used to control chronic pain in elderly patients; however some of these drugs show high rates of adverse drug reactions. Among these are significant clinical problems which impede an effective and safe pain control. This review provides recent data concerning non-steroidal anti-inflammatory drugs (NSAID), acetaminophen, metamizol and flupirtin. Due to their risk profile NSAIDs are less appropriate due to high incidence rates and drug-related risk patterns. Acetaminophen, metamizol and flupirtin may be recommended instead; however a shortcoming of acetaminophen in comparison to NSAIDs is its weaker action to control pain. Metamizol is still banned in some countries due to rare but potentially severe hematological side effects and flupirtin frequently causes unfavorable sedation.
Beschreibung:Gesehen am 15.03.2018
Beschreibung:Online Resource
ISSN:1432-2129
DOI:10.1007/s00482-015-0032-2