Strain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier
Echovirus (E) 30 (E-30) meningitis is characterized by neuroinflammation involving immune cell pleocytosis at the protective barriers of the central nervous system (CNS). In this context, infection of the blood-cerebrospinal fluid barrier (BCSFB), which has been demonstrated to be involved in entero...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
20 February 2018
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| In: |
Journal of neuroinflammation
Year: 2018, Jahrgang: 15 |
| ISSN: | 1742-2094 |
| DOI: | 10.1186/s12974-018-1061-4 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s12974-018-1061-4 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12974-018-1061-4 
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| Verfasserangaben: | Tobias Dahm, Ortwin Adams, Sindy Boettcher, Sabine Diedrich, Vasily Morozov, Grant Hansman, Petra Fallier-Becker, Sebastian Schädler, Claus J. Burkhardt, Christel Weiss, Carolin Stump-Guthier, Hiroshi Ishikawa, Horst Schroten, Christian Schwerk, Tobias Tenenbaum and Henriette Rudolph |
| Zusammenfassung: | Echovirus (E) 30 (E-30) meningitis is characterized by neuroinflammation involving immune cell pleocytosis at the protective barriers of the central nervous system (CNS). In this context, infection of the blood-cerebrospinal fluid barrier (BCSFB), which has been demonstrated to be involved in enteroviral CNS pathogenesis, may affect the tight junction (TJ) and adherens junction (AJ) function and morphology. |
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| Beschreibung: | Gesehen am 04.04.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1742-2094 |
| DOI: | 10.1186/s12974-018-1061-4 |