Impact of oral calcium on mortality of dialysis patients - an underestimated risk?
© The Author 2012. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissionsoup.comcalcification, calcium, haemodialysis, phosphate, phosphate binder...Phosphate is an accepted trigger and promoter of soft tissue calcificati...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
25 April 2012
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| In: |
Nephrology, dialysis, transplantation
Year: 2012, Volume: 27, Issue: 7, Pages: 2628-2633 |
| ISSN: | 1460-2385 |
| DOI: | 10.1093/ndt/gfs077 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1093/ndt/gfs077 Verlag, kostenfrei, Volltext: https://academic.oup.com/ndt/article/27/7/2628/1849242 
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| Author Notes: | Juergen Bommer, Markus Ketteler, Eberhard Ritz |
| Summary: | © The Author 2012. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissionsoup.comcalcification, calcium, haemodialysis, phosphate, phosphate binder...Phosphate is an accepted trigger and promoter of soft tissue calcification. Today, oral calcium-containing phosphate binders are still frequently administered to reduce hyperphosphataemia in patients with reduced renal function. There is, however, increasing evidence that a positive calcium balance and elevated serum calcium concentrations may aggravate soft tissue calcification. Some recent controlled [1, 2] trials as well as recent unpublished observational evidence from Dialysis Outcome and Practice Pattern Study (DOPPS) point to increased mortality in renal patients treated with calcium-containing P binders. Unfortunately, each of these studies has some methodological limitations. Nevertheless, a recent meta-analysis documented an increased risk of myocardial infarction and stroke even in patients without kidney disease when treated with calcium supplements [... |
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| Item Description: | Gesehen am 05.04.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1460-2385 |
| DOI: | 10.1093/ndt/gfs077 |