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Mirror, mirror on the wall: hypercalcemia as a consequence of modern cosmetic treatment with liquid silicone

BACKGROUND: Hypercalcemia is a common problem in clinical practice and can be related to endocrine disorders or malignant disease, especially in elderly patients. Although rare, other causes can also be responsible. CASE REPORT: Granulomatous inflammation of the skin and lymph nodes induced by intra...

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Main Authors: Schanz, Jurik (Author) , Flux, Katharina (Author) , Kircher, Claudia (Author) , Tsioga, Maria (Author) , Hartschuh, Wolfgang (Author) , Nawroth, Peter Paul (Author) , Rudofsky, Gottfried (Author)
Format: Article (Journal)
Language:English
Published: 2012.02.01
In: Medical science monitor
Year: 2012, Volume: 18, Issue: 2, Pages: CS5-7
ISSN:1643-3750
DOI:10.12659/MSM.882450
Online Access:Resolving-System, kostenfrei, Volltext: http://dx.doi.org/10.12659/MSM.882450
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Author Notes:Jurik Schanz, Katharina Flux, Claudia Kircher, Maria Tsioga, Wolfgang Hartschuh, Peter P. Nawroth, Gottfried Rudofsky
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Summary:BACKGROUND: Hypercalcemia is a common problem in clinical practice and can be related to endocrine disorders or malignant disease, especially in elderly patients. Although rare, other causes can also be responsible. CASE REPORT: Granulomatous inflammation of the skin and lymph nodes induced by intravenous or injectable silicone is a rare condition of hypercalcemia that is usually not within the scope of differential diagnosis. Here, we report a 72-year-old woman with symptomatic hypercalcemia related to cosmetic treatment of the neck. Topical applied liquid silicone by means of a focal ultrasound device induced extensive granulomatous inflammation of the skin and local lymph nodes, being the underlying cause for hypercalcemia in this case. CONCLUSIONS: In rare cases, symptomatic hypercalcemia can be caused by silicone due to a severe granulomatous tissue reaction. This is the first time that a transdermal silicone treatment has been reported to cause severe granulomatous tissue inflammation.
Item Description:Gesehen am 11.04.2018
Physical Description:Online Resource
ISSN:1643-3750
DOI:10.12659/MSM.882450

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