Cover Image

Heterotopic abdominal rat heart transplantation as a model to investigate volume dependency of myocardial remodeling

<b></b><p>Heterotopic abdominal rat heart transplantation has been extensively used to investigate ischemic-reperfusion injury, immunological consequences during heart transplantations and also to study remodeling of the myocardium due to volume unloading. We provide a unique revie...

Full description

Saved in:
Bibliographic Details
Main Authors: Benke, Kálmán (Author) , Ruppert, Mihály (Author) , Radovits, Tamás (Author) , Szabó, Gábor (Author)
Format: Article (Journal)
Language:English
Published: March 2017
In: Transplantation
Year: 2017, Volume: 101, Issue: 3, Pages: 498-505
ISSN:1534-6080
DOI:10.1097/TP.0000000000001585
Online Access:Verlag, Volltext: http://dx.doi.org/10.1097/TP.0000000000001585
Verlag, Volltext: https://insights.ovid.com/crossref?an=00007890-201703000-00013
Get full text
Author Notes:Kálmán Benke, Alex Ali Sayour, Csaba Mátyás, Bence Ágg, Balázs Tamás Németh, Attila Oláh, Mihály Ruppert, István Hartyánszky, Zoltán Szabolcs, Tamás Radovits, Béla Merkely, Gábor Szabó
Description
Summary:<b></b><p>Heterotopic abdominal rat heart transplantation has been extensively used to investigate ischemic-reperfusion injury, immunological consequences during heart transplantations and also to study remodeling of the myocardium due to volume unloading. We provide a unique review on the latter and present a summary of the experimental studies on rat heart transplantation to illustrate changes that occur to the myocardium due to volume unloading. We divided the literature based on whether normal or failing rat heart models were used. This analysis may provide a basis to understand the physiological effects of mechanical circulatory support therapy.</p>
Item Description:Gesehen am 11.04.2018
Physical Description:Online Resource
ISSN:1534-6080
DOI:10.1097/TP.0000000000001585

Similar Items