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Impact of robust treatment planning on single- and multi-field optimized plans for proton beam therapy of unilateral head and neck target volumes

Proton beam therapy is promising for the treatment of head and neck cancer (HNC), but it is sensitive to uncertainties in patient positioning and particle range. Studies have shown that the planning target volume (PTV) concept may not be sufficient to ensure robustness of the target coverage. A few...

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Bibliographic Details
Main Authors: Cubillos Mesías, Macarena (Author) , Troost, Esther Gera Cornelia (Author) , Lohaus, Fabian (Author) , Löck, Steffen (Author) , Richter, Christian (Author) , Stützer, Kristin (Author)
Format: Article (Journal)
Language:English
Published: 28 November 2017
In: Radiation oncology
Year: 2017, Volume: 12
ISSN:1748-717X
DOI:10.1186/s13014-017-0931-8
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13014-017-0931-8
Verlag, Volltext: https://doi.org/10.1186/s13014-017-0931-8
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Author Notes:Macarena Cubillos-Mesías, Michael Baumann, Esther G.C. Troost, Fabian Lohaus, Steffen Löck, Christian Richter and Kristin Stützer
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Summary:Proton beam therapy is promising for the treatment of head and neck cancer (HNC), but it is sensitive to uncertainties in patient positioning and particle range. Studies have shown that the planning target volume (PTV) concept may not be sufficient to ensure robustness of the target coverage. A few planning studies have considered irradiation of unilateral HNC targets with protons, but they have only taken into account the dose on the nominal plan, without considering anatomy changes occurring during the treatment course.
Item Description:Gesehen am 11.04.2018
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-017-0931-8

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