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Medication non-adherence and poor glycaemic control in patients with type 2 diabetes mellitus

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Aims Our main aim was to analyse gender differences in the association of adherence and poor glycaemic control (PGC) in a cohort of patients with type 2 diabetes mellitus in Germany. Methods Baseline data of the DIANA-study, a prospective cohort study of type 2 diabetes mellitus patients in South-We...

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Main Authors: Raum, Elke (Author) , Szecsenyi, Joachim (Author)
Format: Article (Journal)
Language:English
Published: 2 July 2012
In: Diabetes research and clinical practice
Year: 2012, Volume: 97, Issue: 3, Pages: 377-384
ISSN:1872-8227
DOI:10.1016/j.diabres.2012.05.026
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.diabres.2012.05.026
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0168822712002148
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Author Notes:Elke Raum, Heike U. Krämer, Gernot Rüter, Dietrich Rothenbacher, Thomas Rosemann, Joachim Szecsenyi, Hermann Brenner
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Summary:Aims Our main aim was to analyse gender differences in the association of adherence and poor glycaemic control (PGC) in a cohort of patients with type 2 diabetes mellitus in Germany. Methods Baseline data of the DIANA-study, a prospective cohort study of type 2 diabetes mellitus patients in South-West Germany, were analysed. Information on medication adherence and factors related to PGC was obtained by self-administered questionnaire. PGC was defined as HbA1c≥7.5%. Bivariate and multivariate analyses using log-binomial regression were employed to assess overall and gender-specific associations of non-adherence and PGC. Results 624 men and 518 women were included in the analyses. In total, 147 men (24%) and 114 women (23%) reported non-adherence to medication. In men, PGC was found in 37% of the participants reporting non-adherence and in 19% reporting adherence (adjusted prevalence ratio (PR)=1.90, 95%-CI: 1.46-2.49). In women, PGC was found in 19% of the participants reporting non-adherence and in 18% reporting adherence (adjusted PR=0.97, 95%-CI: 0.65-1.46). Conclusions Our results show gender-specific differences in the association of adherence and PGC. This underlines the need for efforts to improve glycaemic control in patients with type 2 diabetes mellitus with a particular focus on men.
Item Description:Gesehen am 16.04.2018
Physical Description:Online Resource
ISSN:1872-8227
DOI:10.1016/j.diabres.2012.05.026

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