Effect of self-assembled nanofibrous silk/polycaprolactone layer on the osteoconductivity and mechanical properties of biphasic calcium phosphate scaffolds
Abstract: We here present the first successful report on combining nanostructured silk and poly(ε-caprolactone) (PCL) with a ceramic scaffold to produce a composite scaffold that is highly porous (porosity ∼85%, pore size ∼500 μm, ∼100% interconnectivity), strong and non-brittle with a surface that...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2012
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| In: |
Acta biomaterialia
Year: 2012, Volume: 8, Issue: 1, Pages: 302-312 |
| ISSN: | 1878-7568 |
| DOI: | 10.1016/j.actbio.2011.10.009 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.actbio.2011.10.009 Verlag, Volltext: http://europepmc.org/abstract/med/22023750 |
| Author Notes: | S.I. Roohani-Esfahani, Z.F. Lu, J.J. Li, R. Ellis-Behnke, D.L. Kaplan, H. Zreiqat |
| Summary: | Abstract: We here present the first successful report on combining nanostructured silk and poly(ε-caprolactone) (PCL) with a ceramic scaffold to produce a composite scaffold that is highly porous (porosity ∼85%, pore size ∼500 μm, ∼100% interconnectivity), strong and non-brittle with a surface that resembles extracellular matrix (ECM). |
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| Item Description: | Gesehen am 17.04.2018 Available online 13 October 2011 |
| Physical Description: | Online Resource |
| ISSN: | 1878-7568 |
| DOI: | 10.1016/j.actbio.2011.10.009 |