Effect of self-assembled nanofibrous silk/polycaprolactone layer on the osteoconductivity and mechanical properties of biphasic calcium phosphate scaffolds

Abstract: We here present the first successful report on combining nanostructured silk and poly(ε-caprolactone) (PCL) with a ceramic scaffold to produce a composite scaffold that is highly porous (porosity ∼85%, pore size ∼500 μm, ∼100% interconnectivity), strong and non-brittle with a surface that...

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Bibliographic Details
Main Authors: Roohani-Esfahani, Seyed-Iman (Author) , Ellis-Behnke, Rutledge (Author)
Format: Article (Journal)
Language:English
Published: 2012
In: Acta biomaterialia
Year: 2012, Volume: 8, Issue: 1, Pages: 302-312
ISSN:1878-7568
DOI:10.1016/j.actbio.2011.10.009
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.actbio.2011.10.009
Verlag, Volltext: http://europepmc.org/abstract/med/22023750
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Author Notes:S.I. Roohani-Esfahani, Z.F. Lu, J.J. Li, R. Ellis-Behnke, D.L. Kaplan, H. Zreiqat
Description
Summary:Abstract: We here present the first successful report on combining nanostructured silk and poly(ε-caprolactone) (PCL) with a ceramic scaffold to produce a composite scaffold that is highly porous (porosity ∼85%, pore size ∼500 μm, ∼100% interconnectivity), strong and non-brittle with a surface that resembles extracellular matrix (ECM).
Item Description:Gesehen am 17.04.2018
Available online 13 October 2011
Physical Description:Online Resource
ISSN:1878-7568
DOI:10.1016/j.actbio.2011.10.009