Effect of self-assembled nanofibrous silk/polycaprolactone layer on the osteoconductivity and mechanical properties of biphasic calcium phosphate scaffolds

Abstract: We here present the first successful report on combining nanostructured silk and poly(ε-caprolactone) (PCL) with a ceramic scaffold to produce a composite scaffold that is highly porous (porosity ∼85%, pore size ∼500 μm, ∼100% interconnectivity), strong and non-brittle with a surface that...

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Hauptverfasser: Roohani-Esfahani, Seyed-Iman (VerfasserIn) , Ellis-Behnke, Rutledge (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2012
In: Acta biomaterialia
Year: 2012, Jahrgang: 8, Heft: 1, Pages: 302-312
ISSN:1878-7568
DOI:10.1016/j.actbio.2011.10.009
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/j.actbio.2011.10.009
Verlag, Volltext: http://europepmc.org/abstract/med/22023750
Volltext
Verfasserangaben:S.I. Roohani-Esfahani, Z.F. Lu, J.J. Li, R. Ellis-Behnke, D.L. Kaplan, H. Zreiqat
Beschreibung
Zusammenfassung:Abstract: We here present the first successful report on combining nanostructured silk and poly(ε-caprolactone) (PCL) with a ceramic scaffold to produce a composite scaffold that is highly porous (porosity ∼85%, pore size ∼500 μm, ∼100% interconnectivity), strong and non-brittle with a surface that resembles extracellular matrix (ECM).
Beschreibung:Gesehen am 17.04.2018
Available online 13 October 2011
Beschreibung:Online Resource
ISSN:1878-7568
DOI:10.1016/j.actbio.2011.10.009