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The role of elective supraomohyoidal neck dissection in the treatment of early, node-negative oral squamous cell carcinoma (OSCC): a retrospective analysis of 122 cases

The adequate treatment of the neck in early, clinically node-negative oral squamous cell carcinoma (OSCC) remains controversial. To assess whether elective supraomohyoid neck dissection is reasonable and efficient in early, locally circumscribed OSCC, the outcomes of treatment of 122 patients with a...

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Bibliographic Details
Main Authors: Thiele, Oliver C. (Author) , Seeberger, Robin (Author) , Flechtenmacher, Christa (Author) , Hofele, Christof (Author) , Freier, Kolja (Author)
Format: Article (Journal)
Language:English
Published: Jan 2012
In: Journal of cranio-maxillofacial surgery
Year: 2012, Volume: 40, Issue: 1, Pages: 67-70
ISSN:1878-4119
DOI:10.1016/j.jcms.2011.02.001
Online Access:Verlag, Pay-per-use, Volltext: http://dx.doi.org/10.1016/j.jcms.2011.02.001
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Author Notes:Oliver C. Thiele, Robin Seeberger, Christa Flechtenmacher, Christof Hofele, Kolja Freier
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Summary:The adequate treatment of the neck in early, clinically node-negative oral squamous cell carcinoma (OSCC) remains controversial. To assess whether elective supraomohyoid neck dissection is reasonable and efficient in early, locally circumscribed OSCC, the outcomes of treatment of 122 patients with an OSCC of clinical UICC stage I or II were retrospectively analysed in this study. Occult lymph node metastases were detected in 13.9% (17/122) of cases. They were more frequently found in 12 compared to T1 tumours (19.7% (14/71) vs. 5.9% (3/51), p = 0.03), age, gender and grading had no influence on the prevalence of occult lymph node metastases (all p-values > 0.05) in a multivariate logistic regression model. Subsequent multivariate survival analysis found that the presence of occult metastases was an independent predictor of reduced disease-free survival after 5 years (82.2% vs. 62.5%, p = 0.004, and 61.9% vs. 17.8%, p < 0.001, respectively). Elective supraomohyoid neck dissection detects occult metastases in early, node-negative OSCC, and patients with early OSCC exhibiting occult metastases should be considered as high risk patients, warranting additional therapeutic regimes.
Item Description:Gesehen am 18.04.2018
Physical Description:Online Resource
ISSN:1878-4119
DOI:10.1016/j.jcms.2011.02.001

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