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Which types of mental work demands may be associated with reduced risk of dementia?

Introduction: Previous studies have demonstrated that an overall high level of mental work demands decreased dementia risk. In our study, we investigated whether this effect is driven by specific mental work demands and whether it is exposure dependent. Methods: Patients aged 75+ years were recruite...

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Main Authors: Rodriguez, Francisca S. (Author) , Weyerer, Siegfried (Author)
Format: Article (Journal)
Language:English
Published: April 2017
In: Alzheimer's and dementia
Year: 2017, Volume: 13, Issue: 4, Pages: 431-440
ISSN:1552-5279
DOI:10.1016/j.jalz.2016.08.008
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.jalz.2016.08.008
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1552526016328886
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Author Notes:Francisca S. Then, Tobias Luck, Kathrin Heser, Annette Ernst, Tina Posselt, Birgitt Wiese, Silke Mamone, Christian Brettschneider, Hans-Helmut König, Siegfried Weyerer, Jochen Werle, Edelgard Mösch, Horst Bickel, Angela Fuchs, Michael Pentzek, Wolfgang Maier, Martin Scherer, Michael Wagner, Steffi G. Riedel-Heller, for the AgeCoDe Study Group
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Summary:Introduction: Previous studies have demonstrated that an overall high level of mental work demands decreased dementia risk. In our study, we investigated whether this effect is driven by specific mental work demands and whether it is exposure dependent. Methods: Patients aged 75+ years were recruited from general practitioners and participated in up to seven assessment waves (every 1.5 years) of the longitudinal AgeCoDe study. Analyses of the impact of specific mental work demands on dementia risk were carried out via multivariate regression modeling (n = 2315). Results: We observed a significantly lower dementia risk in individuals with a higher level of “information processing” (HR, 0.888), “pattern detection” (HR, 0.878), “mathematics” (HR, 0.878), and “creativity” (HR, 0.878). Yet, exposure-dependent effects were only significant for “information processing” and “pattern detection.” Discussion: Our longitudinal observations suggest that dementia risk may be reduced by some but not all types of mental work demands.
Item Description:Gesehen am 23.04.2018
Physical Description:Online Resource
ISSN:1552-5279
DOI:10.1016/j.jalz.2016.08.008

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