Recent developments in desensitization of crossmatch-positive kidney transplant recipients
Currently, there are two major options for the successful and timely transplantation of sensitized kidney transplant recipients: (1) avoidance of the sensitization barrier using special allocation programs, or (2) desensitization. In the case of broadly sensitized kidney patients, a combination of b...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
25 July 2012
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| In: |
Transplantation proceedings
Year: 2012, Volume: 44, Issue: 6, Pages: 1648-1651 |
| ISSN: | 1873-2623 |
| DOI: | 10.1016/j.transproceed.2012.04.006 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.transproceed.2012.04.006 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0041134512004022 
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| Author Notes: | C. Morath, G. Opelz, M. Zeier, C. Süsal |
| Summary: | Currently, there are two major options for the successful and timely transplantation of sensitized kidney transplant recipients: (1) avoidance of the sensitization barrier using special allocation programs, or (2) desensitization. In the case of broadly sensitized kidney patients, a combination of both options might be necessary. This review focuses on new advances in desensitization of crossmatch-positive kidney transplant recipients which include immunoadsorption and the administration of new substances such as the complement C5 inhibitor eculizumab. Finally, integrated algorithms that combine different measures are acknowledged. |
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| Item Description: | Gesehen am 07.05.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1873-2623 |
| DOI: | 10.1016/j.transproceed.2012.04.006 |