Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment
Calprotectin consists of the Ca2+-binding proteins S100a8 and S100a9 that are induced in epithelial cells in response to tissue damage and infection. Both proteins are also secreted by activated innate immune cells and numerous studies demonstrate their crucial role in pathological conditions of acu...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2012
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| In: |
Cell communication and signaling
Year: 2012, Volume: 10, Pages: 40 |
| ISSN: | 1478-811X |
| DOI: | 10.1186/1478-811X-10-40 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/1478-811X-10-40 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/1478-811X-10-40 
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| Author Notes: | Lars Wiechert, Julia Németh, Tobias Pusterla, Christine Bauer, Aurora De Ponti, Sandra Manthey, Silke Marhenke, Arndt Vogel, Ursula Klingmüller, Jochen Hess, and Peter Angel |
| Summary: | Calprotectin consists of the Ca2+-binding proteins S100a8 and S100a9 that are induced in epithelial cells in response to tissue damage and infection. Both proteins are also secreted by activated innate immune cells and numerous studies demonstrate their crucial role in pathological conditions of acute and chronic inflammation. |
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| Item Description: | Gesehen am 07.05.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1478-811X |
| DOI: | 10.1186/1478-811X-10-40 |