Effect of a novel nonviral gene delivery of BMP-2 on bone healing

Background. Gene therapeutic drug delivery approaches have been introduced to improve the efficiency of growth factors at the site of interest. This study investigated the efficacy and safety of a new nonviral copolymer-protected gene vector (COPROG) for the stimulation of bone healing. Methods. In...

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Bibliographic Details
Main Authors: Schwabe, Philipp (Author) , Schmidmaier, Gerhard (Author)
Format: Article (Journal)
Language:English
Published: 30 September 2012
In: The ScientificWorld journal

ISSN:1537-744X
DOI:10.1100/2012/560142
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1100/2012/560142
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/10.1100/2012/560142
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Author Notes:P. Schwabe, S. Greiner, R. Ganzert, J. Eberhart, K. Dähn, A. Stemberger, C. Plank, G. Schmidmaier, and B. Wildemann
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Summary:Background. Gene therapeutic drug delivery approaches have been introduced to improve the efficiency of growth factors at the site of interest. This study investigated the efficacy and safety of a new nonviral copolymer-protected gene vector (COPROG) for the stimulation of bone healing. Methods. In vitro, rat osteoblasts were transfected with COPROG
Item Description:Gesehen am 08.05.2018
Physical Description:Online Resource
ISSN:1537-744X
DOI:10.1100/2012/560142