Effect of a novel nonviral gene delivery of BMP-2 on bone healing
Background. Gene therapeutic drug delivery approaches have been introduced to improve the efficiency of growth factors at the site of interest. This study investigated the efficacy and safety of a new nonviral copolymer-protected gene vector (COPROG) for the stimulation of bone healing. Methods. In...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
30 September 2012
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| In: |
The ScientificWorld journal
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| ISSN: | 1537-744X |
| DOI: | 10.1100/2012/560142 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1100/2012/560142 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/10.1100/2012/560142 
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| Verfasserangaben: | P. Schwabe, S. Greiner, R. Ganzert, J. Eberhart, K. Dähn, A. Stemberger, C. Plank, G. Schmidmaier, and B. Wildemann |
| Zusammenfassung: | Background. Gene therapeutic drug delivery approaches have been introduced to improve the efficiency of growth factors at the site of interest. This study investigated the efficacy and safety of a new nonviral copolymer-protected gene vector (COPROG) for the stimulation of bone healing. Methods. In vitro, rat osteoblasts were transfected with COPROG |
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| Beschreibung: | Gesehen am 08.05.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1537-744X |
| DOI: | 10.1100/2012/560142 |