Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien
Novel simplified side chains of the potent RNA polymerase inhibitor etnangien were designed, synthesized and evaluated for antibacterial activity against Gram-positive bacteria and one Gram-negative bacterium.
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
14 July 2012
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| In: |
Bioorganic & medicinal chemistry letters
Year: 2012, Volume: 22, Issue: 17, Pages: 5731-5734 |
| ISSN: | 1464-3405 |
| DOI: | 10.1016/j.bmcl.2012.06.070 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.bmcl.2012.06.070
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| Author Notes: | Mario Altendorfer, Herbert Irschik, Dirk Menche |
| Summary: | Novel simplified side chains of the potent RNA polymerase inhibitor etnangien were designed, synthesized and evaluated for antibacterial activity against Gram-positive bacteria and one Gram-negative bacterium. |
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| Item Description: | Gesehen am 09.05.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1464-3405 |
| DOI: | 10.1016/j.bmcl.2012.06.070 |