Cover Image

Cryo-Electron Microscopy Modeling by the Molecular Dynamics Flexible Fitting Method

The increasing power and popularity of cryo-electron microscopy (cryo-EM) in structural biology brought about the development of so-called hybrid methods, which permit the interpretation of cryo-EM density maps beyond their nominal resolution in terms of atomic models. The Cryo-EM Modeling Challenge...

Full description

Saved in:
Bibliographic Details
Main Authors: Chan, Kwok-Yan (Author) , Trabuco, Leonardo G. (Author) , Schreiner, Eduard (Author) , Schulten, Klaus (Author)
Format: Article (Journal)
Language:English
Published: 28 February 2012
In: Biopolymers
Year: 2012, Volume: 97, Issue: 9, Pages: 678-686
ISSN:1097-0282
DOI:10.1002/bip.22042
Online Access:Verlag, Volltext: http://dx.doi.org/10.1002/bip.22042
Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/bip.22042
Get full text
Author Notes:Kwok-Yan Chan, Leonardo G. Trabuco, Eduard Schreiner, Klaus Schulten

MARC

LEADER 00000caa a2200000 c 4500
001 1575066726
003 DE-627
005 20220814141428.0
007 cr uuu---uuuuu
008 180515s2012 xx |||||o 00| ||eng c
024 7 |a 10.1002/bip.22042  |2 doi 
035 |a (DE-627)1575066726 
035 |a (DE-576)505066726 
035 |a (DE-599)BSZ505066726 
035 |a (OCoLC)1341009633 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 29  |2 sdnb 
100 1 |a Chan, Kwok-Yan  |e VerfasserIn  |0 (DE-588)1159599696  |0 (DE-627)1022281976  |0 (DE-576)505067676  |4 aut 
245 1 0 |a Cryo-Electron Microscopy Modeling by the Molecular Dynamics Flexible Fitting Method  |c Kwok-Yan Chan, Leonardo G. Trabuco, Eduard Schreiner, Klaus Schulten 
264 1 |c 28 February 2012 
300 |a 25 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 15.05.2018 
520 |a The increasing power and popularity of cryo-electron microscopy (cryo-EM) in structural biology brought about the development of so-called hybrid methods, which permit the interpretation of cryo-EM density maps beyond their nominal resolution in terms of atomic models. The Cryo-EM Modeling Challenge 2010 is the first community effort to bring together developers of hybrid methods as well as cryo-EM experimentalists. Participating in the challenge, the molecular dynamics flexible fitting (MDFF) method was applied to a number of cryo-EM density maps. The results are described here with special emphasis on the use of symmetry-based restraints to improve the quality of atomic models derived from density maps of symmetric complexes; on a comparison of the stereochemical quality of atomic models resulting from different hybrid methods; and on application of MDFF to electron crystallography data. © 2012 Wiley Periodicals, Inc. Biopolymers 97: 678-686, 2012. 
650 4 |a cryo-electron microscopy 
650 4 |a Cryo-EM Modeling Challenge 2010 
650 4 |a molecular dynamics flexible fitting (MDFF) 
700 1 |a Trabuco, Leonardo G.  |e VerfasserIn  |0 (DE-588)1044138068  |0 (DE-627)771570708  |0 (DE-576)39673734X  |4 aut 
700 1 |a Schreiner, Eduard  |d 1976-  |e VerfasserIn  |0 (DE-588)133596192  |0 (DE-627)549554440  |0 (DE-576)299959058  |4 aut 
700 1 |a Schulten, Klaus  |d 1947-2016  |e VerfasserIn  |0 (DE-588)1031699198  |0 (DE-627)737144424  |0 (DE-576)379398265  |4 aut 
773 0 8 |i Enthalten in  |t Biopolymers  |d New York, NY : Wiley, 1963  |g 97(2012), 9, Seite 678-686  |h Online-Ressource  |w (DE-627)271598115  |w (DE-600)1480801-8  |w (DE-576)09408257X  |x 1097-0282  |7 nnas  |a Cryo-Electron Microscopy Modeling by the Molecular Dynamics Flexible Fitting Method 
773 1 8 |g volume:97  |g year:2012  |g number:9  |g pages:678-686  |g extent:25  |a Cryo-Electron Microscopy Modeling by the Molecular Dynamics Flexible Fitting Method 
856 4 0 |u http://dx.doi.org/10.1002/bip.22042  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u https://onlinelibrary.wiley.com/doi/abs/10.1002/bip.22042  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20180515 
993 |a Article 
994 |a 2012 
998 |g 1044138068  |a Trabuco, Leonardo G.  |m 1044138068:Trabuco, Leonardo G.  |d 700000  |d 718000  |e 700000PT1044138068  |e 718000PT1044138068  |k 0/700000/  |k 1/700000/718000/  |p 2 
999 |a KXP-PPN1575066726  |e 3009334346 
BIB |a Y 
SER |a journal 
JSO |a {"name":{"displayForm":["Kwok-Yan Chan, Leonardo G. Trabuco, Eduard Schreiner, Klaus Schulten"]},"origin":[{"dateIssuedDisp":"28 February 2012","dateIssuedKey":"2012"}],"id":{"doi":["10.1002/bip.22042"],"eki":["1575066726"]},"physDesc":[{"extent":"25 S."}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedDisp":"1963-","dateIssuedKey":"1963","publisher":"Wiley","publisherPlace":"New York, NY"}],"id":{"zdb":["1480801-8"],"eki":["271598115"],"doi":["10.1002/(ISSN)1097-0282"],"issn":["1097-0282"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"note":["Gesehen am 06.03.2023","Fortsetzung der Druck-Ausgabe"],"disp":"Cryo-Electron Microscopy Modeling by the Molecular Dynamics Flexible Fitting MethodBiopolymers","recId":"271598115","language":["eng"],"pubHistory":["1.1963 -"],"part":{"issue":"9","pages":"678-686","year":"2012","extent":"25","volume":"97","text":"97(2012), 9, Seite 678-686"},"title":[{"title":"Biopolymers","title_sort":"Biopolymers"}]}],"person":[{"display":"Chan, Kwok-Yan","roleDisplay":"VerfasserIn","role":"aut","family":"Chan","given":"Kwok-Yan"},{"given":"Leonardo G.","family":"Trabuco","role":"aut","roleDisplay":"VerfasserIn","display":"Trabuco, Leonardo G."},{"role":"aut","display":"Schreiner, Eduard","roleDisplay":"VerfasserIn","given":"Eduard","family":"Schreiner"},{"family":"Schulten","given":"Klaus","roleDisplay":"VerfasserIn","display":"Schulten, Klaus","role":"aut"}],"title":[{"title_sort":"Cryo-Electron Microscopy Modeling by the Molecular Dynamics Flexible Fitting Method","title":"Cryo-Electron Microscopy Modeling by the Molecular Dynamics Flexible Fitting Method"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 15.05.2018"],"language":["eng"],"recId":"1575066726"} 
SRT |a CHANKWOKYACRYOELECTR2820 

Similar Items