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Data on microcirculatory parameters of GTS- 21 treated rats assessed by intravital microscopy

This article contains animal experimental data associated with the research article entitled “GTS-21 reduces microvascular permeability during experimental endotoxemia” (Schmidt et al., 2017) (supplementary datasets of baseline intravital microscopic measurements, baseline TNF-α levels and vital pa...

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Hauptverfasser: Schmidt, Karsten (VerfasserIn) , Bhakdisongkhram, Sukanya (VerfasserIn) , Uhle, Florian (VerfasserIn) , Philipsenburg, Christoph (VerfasserIn) , Živković, Aleksandar (VerfasserIn) , Brenner, Thorsten (VerfasserIn) , Motsch, Johann (VerfasserIn) , Weigand, Markus A. (VerfasserIn) , Hofer, Stefan (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 23 September 2017
In: Data in Brief
Year: 2017, Jahrgang: 15, Pages: 228-233
ISSN:2352-3409
DOI:10.1016/j.dib.2017.09.045
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/j.dib.2017.09.045
Verlag, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633251/
Volltext
Verfasserangaben:Karsten Schmidt, Sukanya Bhakdisongkhram, Florian Uhle, Christoph Philipsenburg, Aleksandar R. Zivkovic, Thorsten Brenner, Johann Motsch, Markus A. Weigand, Stefan Hofer
Beschreibung
Zusammenfassung:This article contains animal experimental data associated with the research article entitled “GTS-21 reduces microvascular permeability during experimental endotoxemia” (Schmidt et al., 2017) (supplementary datasets of baseline intravital microscopic measurements, baseline TNF-α levels and vital parameters of the evaluated experimental groups are provided). Beneficial anti-inflammatory effects of cholinergic mediators on microvascular inflammation have been demonstrated by intravital microscopic investigations (Schmidt et al., 2015) , therefore we evaluated the effect of the cholinergic mediator GTS-21 on microcirculatory alterations during endotoxemia . The data regarding microcirculatory effects of GTS-21 treatment ((3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride; 1 mg/kg; i.v.) in non-endotoxemic animals are presented in this article.
Beschreibung:Gesehen am 23.05.2018
Beschreibung:Online Resource
ISSN:2352-3409
DOI:10.1016/j.dib.2017.09.045

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