Data on microcirculatory parameters of GTS- 21 treated rats assessed by intravital microscopy
This article contains animal experimental data associated with the research article entitled “GTS-21 reduces microvascular permeability during experimental endotoxemia” (Schmidt et al., 2017) (supplementary datasets of baseline intravital microscopic measurements, baseline TNF-α levels and vital pa...
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| Main Authors: | , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
23 September 2017
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| In: |
Data in Brief
Year: 2017, Volume: 15, Pages: 228-233 |
| ISSN: | 2352-3409 |
| DOI: | 10.1016/j.dib.2017.09.045 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.dib.2017.09.045 Verlag, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633251/ 
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| Author Notes: | Karsten Schmidt, Sukanya Bhakdisongkhram, Florian Uhle, Christoph Philipsenburg, Aleksandar R. Zivkovic, Thorsten Brenner, Johann Motsch, Markus A. Weigand, Stefan Hofer |
| Summary: | This article contains animal experimental data associated with the research article entitled “GTS-21 reduces microvascular permeability during experimental endotoxemia” (Schmidt et al., 2017) (supplementary datasets of baseline intravital microscopic measurements, baseline TNF-α levels and vital parameters of the evaluated experimental groups are provided). Beneficial anti-inflammatory effects of cholinergic mediators on microvascular inflammation have been demonstrated by intravital microscopic investigations (Schmidt et al., 2015) , therefore we evaluated the effect of the cholinergic mediator GTS-21 on microcirculatory alterations during endotoxemia . The data regarding microcirculatory effects of GTS-21 treatment ((3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride; 1 mg/kg; i.v.) in non-endotoxemic animals are presented in this article. |
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| Item Description: | Gesehen am 23.05.2018 |
| Physical Description: | Online Resource |
| ISSN: | 2352-3409 |
| DOI: | 10.1016/j.dib.2017.09.045 |