Aqueous microwave-assisted one-pot synthesis of N-substituted rhodanines
Two aqueous, one-pot, microwave-assisted methods for the rapid synthesis of N-substituted rhodanines from amine substrates are described. Alkyl- and benzylamines could be converted into the corresponding rhodanines with an atom-efficient one-pot, three-step protocol based on carbon disulfide and chl...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
6 July 2012
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| In: |
Tetrahedron letters
Year: 2012, Jahrgang: 53, Heft: 39, Pages: 5197-5201 |
| ISSN: | 1873-3581 |
| DOI: | 10.1016/j.tetlet.2012.07.002 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.tetlet.2012.07.002 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0040403912011689 
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| Verfasserangaben: | Christoph Nitsche, Christian D. Klein |
| Zusammenfassung: | Two aqueous, one-pot, microwave-assisted methods for the rapid synthesis of N-substituted rhodanines from amine substrates are described. Alkyl- and benzylamines could be converted into the corresponding rhodanines with an atom-efficient one-pot, three-step protocol based on carbon disulfide and chloroacetic acid in short reaction times and good to excellent yields. An alternative, microwave-assisted one-pot, one-step protocol using bis(carboxymethyl)trithiocarbonate in water was developed for the synthesis of N-arylrhodanines from anilines. |
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| Beschreibung: | Gesehen am 29.05.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1873-3581 |
| DOI: | 10.1016/j.tetlet.2012.07.002 |