Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias: the time is now (?)

Therapeutic advances in the management of idiopathic pulmonary fibrosis (IPF) has led to improved outcomes with the use of the antifibrotic agents pirfenidone and nintedanib, with a number of randomized studies demonstrating benefits in slowing disease progression in IPF. However, treatment of other...

Full description

Saved in:
Bibliographic Details
Main Authors: Kreuter, Michael (Author) , Wälscher, Julia (Author) , Behr, Jürgen (Author)
Format: Article (Journal)
Language:English
Published: 2017
In: Current opinion in pulmonary medicine
Year: 2017, Volume: 23, Issue: 5, Pages: 418-425
ISSN:1531-6971
DOI:10.1097/MCP.0000000000000408
Online Access:Verlag, Volltext: http://dx.doi.org/10.1097/MCP.0000000000000408
Verlag, Volltext: https://insights.ovid.com/pubmed?pmid=28622199
Get full text
Author Notes:Michael Kreuter, Julia Wälscher, Jürgen Behr

MARC

LEADER 00000caa a2200000 c 4500
001 1576121534
003 DE-627
005 20230427042927.0
007 cr uuu---uuuuu
008 180607s2017 xx |||||o 00| ||eng c
024 7 |a 10.1097/MCP.0000000000000408  |2 doi 
035 |a (DE-627)1576121534 
035 |a (DE-576)506121534 
035 |a (DE-599)BSZ506121534 
035 |a (OCoLC)1341010792 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Kreuter, Michael  |d 1972-  |e VerfasserIn  |0 (DE-588)122645995  |0 (DE-627)082066795  |0 (DE-576)293362742  |4 aut 
245 1 0 |a Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias  |b the time is now (?)  |c Michael Kreuter, Julia Wälscher, Jürgen Behr 
264 1 |c 2017 
300 |a 8 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 07.06.2018 
520 |a Therapeutic advances in the management of idiopathic pulmonary fibrosis (IPF) has led to improved outcomes with the use of the antifibrotic agents pirfenidone and nintedanib, with a number of randomized studies demonstrating benefits in slowing disease progression in IPF. However, treatment of other fibrosing interstitial lung diseases (ILD) remains challenging. Observational and uncontrolled studies investigating pirfenidone and nintedanib in non-IPF ILDs suggest potential benefits, although the data is weak. A number of randomized controlled trials evaluating pirfenidone and nintedanib in a variety of fibrosing ILDs are currently enrolling or planned. The review will discuss the rationale for use of established antifibrotic drugs approved for IPF for use in non-IPF ILD, describe supportive data from observational studies and ongoing clinical trials. 
700 1 |a Wälscher, Julia  |d 1983-  |e VerfasserIn  |0 (DE-588)1080160175  |0 (DE-627)843891327  |0 (DE-576)453362141  |4 aut 
700 1 |a Behr, Jürgen  |d 1974-  |e VerfasserIn  |0 (DE-588)136199275  |0 (DE-627)577711644  |0 (DE-576)300891350  |4 aut 
773 0 8 |i Enthalten in  |t Current opinion in pulmonary medicine  |d Philadelphia, Pa. : Lippincott Williams & Wilkins, 1995  |g 23(2017), 5, Seite 418-425  |h Online-Ressource  |w (DE-627)324455763  |w (DE-600)2026974-2  |w (DE-576)093981104  |x 1531-6971  |7 nnas  |a Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias the time is now (?) 
773 1 8 |g volume:23  |g year:2017  |g number:5  |g pages:418-425  |g extent:8  |a Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias the time is now (?) 
856 4 0 |u http://dx.doi.org/10.1097/MCP.0000000000000408  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u https://insights.ovid.com/pubmed?pmid=28622199  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20180607 
993 |a Article 
994 |a 2017 
998 |g 1080160175  |a Wälscher, Julia  |m 1080160175:Wälscher, Julia  |d 910000  |d 950000  |d 950900  |e 910000PW1080160175  |e 950000PW1080160175  |e 950900PW1080160175  |k 0/910000/  |k 1/910000/950000/  |k 2/910000/950000/950900/  |p 2 
998 |g 122645995  |a Kreuter, Michael  |m 122645995:Kreuter, Michael  |d 910000  |d 950000  |d 950900  |d 50000  |e 910000PK122645995  |e 950000PK122645995  |e 950900PK122645995  |e 50000PK122645995  |k 0/910000/  |k 1/910000/950000/  |k 2/910000/950000/950900/  |k 0/50000/  |p 1  |x j 
999 |a KXP-PPN1576121534  |e 3012017895 
BIB |a Y 
SER |a journal 
JSO |a {"title":[{"subtitle":"the time is now (?)","title":"Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias","title_sort":"Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias"}],"id":{"eki":["1576121534"],"doi":["10.1097/MCP.0000000000000408"]},"name":{"displayForm":["Michael Kreuter, Julia Wälscher, Jürgen Behr"]},"physDesc":[{"extent":"8 S."}],"origin":[{"dateIssuedKey":"2017","dateIssuedDisp":"2017"}],"relHost":[{"language":["eng"],"disp":"Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias the time is now (?)Current opinion in pulmonary medicine","physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisher":"Lippincott Williams & Wilkins ; Ovid","dateIssuedDisp":"1995-","dateIssuedKey":"1995","publisherPlace":"Philadelphia, Pa. ; [Erscheinungsort nicht ermittelbar]"}],"title":[{"title":"Current opinion in pulmonary medicine","title_sort":"Current opinion in pulmonary medicine"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"pubHistory":["1.1995 -"],"note":["Gesehen am 24.01.05"],"part":{"text":"23(2017), 5, Seite 418-425","year":"2017","extent":"8","pages":"418-425","volume":"23","issue":"5"},"recId":"324455763","id":{"eki":["324455763"],"zdb":["2026974-2"],"issn":["1531-6971"]}}],"person":[{"family":"Kreuter","given":"Michael","roleDisplay":"VerfasserIn","role":"aut","display":"Kreuter, Michael"},{"display":"Wälscher, Julia","given":"Julia","role":"aut","roleDisplay":"VerfasserIn","family":"Wälscher"},{"family":"Behr","display":"Behr, Jürgen","given":"Jürgen","role":"aut","roleDisplay":"VerfasserIn"}],"language":["eng"],"note":["Gesehen am 07.06.2018"],"recId":"1576121534","type":{"media":"Online-Ressource","bibl":"article-journal"}} 
SRT |a KREUTERMICANTIFIBROT2017