Comparison and outcome analysis of patients with takotsubo cardiomyopathy triggered by emotional stress or physical stress
Background: Previous studies revealed that Takotsubo cardiomyopathy (TTC) is triggered by physical and emotional stresses. This study was performed to determine the short- and long-term prognostic impact of emotional- and physical stress associated with TTC. Methods and results: Our institutional da...
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| Main Authors: | , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
27 April 2017
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| In: |
Frontiers in psychology
Year: 2017, Volume: 8 |
| ISSN: | 1664-1078 |
| DOI: | 10.3389/fpsyg.2017.00527 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.3389/fpsyg.2017.00527 Verlag, kostenfrei, Volltext: https://www.frontiersin.org/articles/10.3389/fpsyg.2017.00527/full 
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| Author Notes: | Konstantinos Giannakopoulos, Ibrahim El-Battrawy, Katja Schramm, Uzair Ansari, Ursula Hoffmann, Martin Borggrefe and Ibrahim Akin |
| Summary: | Background: Previous studies revealed that Takotsubo cardiomyopathy (TTC) is triggered by physical and emotional stresses. This study was performed to determine the short- and long-term prognostic impact of emotional- and physical stress associated with TTC. Methods and results: Our institutional database constituted a collective of 84 patients diagnosed with TTC between 2003 and 2015. The patients were divided into two groups as per the presence of emotional stress (n=24, 21%) or physical stress (n=60, 52.6%). The endpoint was a composite of in-hospital events (thromboembolic events and life-threatening arrhythmias), myocardial infarction, all-cause of mortality, re-hospitalization due to heart failure, stroke, and recurrence of TTC. A Kaplan-Meier analysis indicated a significantly lower event-free survival rate over a mean follow-up of 5 years in the emotional group than the physical stress group (log-rank, p<0.01). Multivariate Cox regression analysis revealed only emotional stress (HR 0.4, 95% CI: 0.2-0.9, p<0.05) as a negative independent predictor of the primary endpoint. Conclusion: Rates of in-hospital events and short- as well as long-term events were significantly lower in TTC patients suffering from emotional stress as compared to patients with physical stress. |
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| Item Description: | Gesehen am 08.06.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1664-1078 |
| DOI: | 10.3389/fpsyg.2017.00527 |