Impact of patient information leaflets on pain medication intake behavior: a pilot study
Introduction: Patient information leaflets on pain medication primarily list side effects while positive effects and action mechanisms remain underrepresented. Nocebo research has shown that negative instructions can lower analgesic effects. Objectives: Research on information leaflets and their inf...
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| In: |
Pain reports
Year: 2017, Jahrgang: 2, Heft: 6 |
| ISSN: | 2471-2531 |
| DOI: | 10.1097/PR9.0000000000000620 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1097/PR9.0000000000000620 Verlag, kostenfrei, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741322/ 
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| Verfasserangaben: | Julia Schmitz, Sandra Kamping, Janine Wiegratz, Maike Müller, Jan Stork, Luana Colloca, Herta Flor, Regine Klinger |
| Zusammenfassung: | Introduction: Patient information leaflets on pain medication primarily list side effects while positive effects and action mechanisms remain underrepresented. Nocebo research has shown that negative instructions can lower analgesic effects. Objectives: Research on information leaflets and their influence on mood, memory of side effects, and intake behavior of healthy participants is needed. Methods: To determine the ratio of positive to negative phrases, 18 information leaflets of common, over-the-market analgesics were examined of which 1 was selected. In a randomized, controlled study design, 18 healthy participants read this leaflet while 18 control group participants read a matched, neutral leaflet of an electrical device. Collected data concerned the recall of positive and negative contents, mood, anxiety, and the willingness to buy and take the drug. Results: All examined leaflets listed significantly more side effects than positive effects (t17 5 5.82, P , 0.01). After reading the analgesic leaflet, participants showed a trend towards more negative mood (F1,34 5 3.78, P 5 0.06, hp 2 5 0.1), a lower intention to buy [x2 (1, n 5 36) 5 12.5, P , 0.01], a higher unwillingness to take the medication [x2 (1, n 5 36) 5 7.2, P , 0.01], and even a greater recall for side effects than positive effects (t17 5 7.47, P , 0.01). Conclusion: Reading the patient information leaflets can increase fear and lower the intention to buy and the willingness to takeNegative wording in package information leaflets of pain medication is associated with a tendency to evoke negative emotions and lower willing to take medication. |
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| Beschreibung: | Published online 2017 Sep 29 Gesehen am 14.06.2016 |
| Beschreibung: | Online Resource |
| ISSN: | 2471-2531 |
| DOI: | 10.1097/PR9.0000000000000620 |