Free-breathing sparse sampling cine MR imaging with iterative reconstruction for the assessment of left ventricular function and mass at 3.0 T
PurposeTo prospectively evaluate the accuracy of left ventricle (LV) analysis with a two-dimensional real-time cine true fast imaging with steady-state precession (trueFISP) magnetic resonance (MR) imaging sequence featuring sparse data sampling with iterative reconstruction (SSIR) performed with an...
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| Main Authors: | , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
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| In: |
Radiology
Year: 2016, Volume: 282, Issue: 1, Pages: 74-83 |
| ISSN: | 1527-1315 |
| DOI: | 10.1148/radiol.2016151002 |
| Online Access: | Verlag, LF, Volltext: http://dx.doi.org/10.1148/radiol.2016151002 Verlag, LF, Volltext: https://pubs.rsna.org/doi/10.1148/radiol.2016151002 
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| Author Notes: | Sonja Sudarski, MD, Thomas Henzler, MD, Holger Haubenreisser, MD, Christina Dösch, MD, Michael O. Zenge, PhD, Michaela Schmidt, RT, Mariappan S. Nadar, PhD, Martin Borggrefe, MD, Stefan O. Schoenberg, MD, Theano Papavassiliu, MD |
| Summary: | PurposeTo prospectively evaluate the accuracy of left ventricle (LV) analysis with a two-dimensional real-time cine true fast imaging with steady-state precession (trueFISP) magnetic resonance (MR) imaging sequence featuring sparse data sampling with iterative reconstruction (SSIR) performed with and without breath-hold (BH) commands at 3.0 T.Materials and MethodsTen control subjects (mean age, 35 years; range, 25-56 years) and 60 patients scheduled to undergo a routine cardiac examination that included LV analysis (mean age, 58 years; range, 20-86 years) underwent a fully sampled segmented multiple BH cine sequence (standard of reference) and a prototype undersampled SSIR sequence performed during a single BH and during free breathing (non-BH imaging). Quantitative analysis of LV function and mass was performed. Linear regression, Bland-Altman analysis, and paired t testing were performed.ResultsSimilar to the results in control subjects, analysis of the 60 patients showed excellent correlation with the standard of reference for single-BH SSIR (r = 0.93-0.99) and non-BH SSIR (r = 0.92-0.98) for LV ejection fraction (EF), volume, and mass (P < .0001 for all). Irrespective of breath holding, LV end-diastolic mass was overestimated with SSIR (standard of reference: 163.9 g ± 58.9, single-BH SSIR: 178.5 g ± 62.0 [P < .0001], non-BH SSIR: 175.3 g ± 63.7 [P < .0001]); the other parameters were not significantly different (EF: 49.3% ± 11.9 with standard of reference, 48.8% ± 11.8 with single-BH SSIR, 48.8% ± 11 with non-BH SSIR; P = .03 and P = .12, respectively). Bland-Altman analysis showed similar measurement errors for single-BH SSIR and non-BH SSIR when compared with standard of reference measurements for EF, volume, and mass.ConclusionAssessment of LV function with SSIR at 3.0 T is noninferior to the standard of reference irrespective of BH commands. LV mass, however, is overestimated with SSIR.© RSNA, 2016Online supplemental material is available for this article. |
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| Item Description: | Published online: Jul 11 2016 Gesehen am 14.06.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1527-1315 |
| DOI: | 10.1148/radiol.2016151002 |