Polarity-specific transcranial direct current stimulation effects on object-selective neural responses in the inferior parietal lobe
Neuromodulation techniques such as transcranial direct current stimulation (tDCS) are routinely used for treating neurological and neuropsychiatric disorders, and for enhancement of cognitive abilities. Recently, their effectiveness in modulating behavioral and neural responses has been questioned....
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
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| In: |
Cortex
Year: 2017, Volume: 94, Pages: 176-181 |
| ISSN: | 1973-8102 |
| DOI: | 10.1016/j.cortex.2017.07.001 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.cortex.2017.07.001 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0010945217302204 
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| Author Notes: | Jorge Almeida, Ana R. Martins, Fredrik Bergström, Lénia Amaral, Andreia Freixo, Ana Ganho-Ávila, Stephanie Kristensen, Dongha Lee, Joana Nogueira and Michaela Ruttorf |
| Summary: | Neuromodulation techniques such as transcranial direct current stimulation (tDCS) are routinely used for treating neurological and neuropsychiatric disorders, and for enhancement of cognitive abilities. Recently, their effectiveness in modulating behavioral and neural responses has been questioned. Here we use excitatory and inhibitory tDCS prior to a functional magnetic resonance imaging (fMRI) experiment to show that neural responses for an area's preferred stimuli depend on the polarity of stimulation. This is an important, yet overlooked, data point in demonstrating the effectiveness of these stimulation techniques. Our results show that response preferences in the target area are dependent on the polarity of the tDCS session preceding the fMRI experiment - these preferences are less distinct in the cathodal than in the anodal session. As such, we show unequivocally that tDCS modulates neural responses. This result is of the utmost importance in demonstrating the effectiveness of tDCS for clinical and experimental purposes. |
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| Item Description: | Published online 13 July 2017 Gesehen am 18.06.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1973-8102 |
| DOI: | 10.1016/j.cortex.2017.07.001 |