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The localization and risk factors of squamous cell carcinoma in the oral cavity: a retrospective study of 1501 cases

Head and neck cancer is the tenth leading cause of cancer mortality. Ninety percent of tumours in the oral cavity are squamous cell carcinomas. Information about the exact localisation of OSCC is missing in the literature. In the present study, we retrospectively analysed a total of 1501 OSCC patien...

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Bibliographic Details
Main Authors: Sundermann, Britta Vanessa (Author) , Uhlmann, Lorenz (Author) , Hoffmann, Jürgen (Author) , Freier, Kolja (Author) , Thiele, Oliver C. (Author)
Format: Article (Journal)
Language:English
Published: 2018
In: Journal of cranio-maxillofacial surgery
Year: 2018, Volume: 46, Issue: 2, Pages: 177-182
ISSN:1878-4119
DOI:10.1016/j.jcms.2017.10.019
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.jcms.2017.10.019
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1010518217303694
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Author Notes:Britta V. Sundermann, Lorenz Uhlmann, Jürgen Hoffmann, Kolja Freier, Oliver C. Thiele
Description
Summary:Head and neck cancer is the tenth leading cause of cancer mortality. Ninety percent of tumours in the oral cavity are squamous cell carcinomas. Information about the exact localisation of OSCC is missing in the literature. In the present study, we retrospectively analysed a total of 1501 OSCC patients, who were treated between 1975 and 2009. The purpose of this study was to examine the localisation of OSCC tumours and to analyse the influence of various parameters on tumour localisation. 71.5% of these patients were male and 28.5% were female. The mean age was 60 years. The most common sites of OSCC occurrence were the floor of the mouth and the anterior base of the mouth. The hard palate was the most affected anatomical area of the maxilla. Descriptive statistical analysis, chi-square testing and a multivariate analysis using a multinomial logistical model showed a significant correlation of younger age and female gender with tumour occurrence in the maxilla and the tongue. We provide a very detailed anatomical mapping of OSCC.
Item Description:Published online: 31 October 2017
Gesehen am 19.06.2018
Physical Description:Online Resource
ISSN:1878-4119
DOI:10.1016/j.jcms.2017.10.019

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