Unmasked: when a clinically malignant disease turns out infectious : a rare case of tularemia

This article reports on a 62-year-old man, who presented with cervical mass and rather nonspecific symptoms. The medical history and clinical workup initially favored a malignant disease such as a carcinoma of unknown primary as the underlying cause. Eventually, the patient was diagnosed with a gran...

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Main Authors: Bulut, Cem (Author) , Dyckhoff, Gerhard (Author) , Penzel, Roland (Author) , Plinkert, Peter K. (Author) , Simon, Christian (Author) , Weichert, Wilko (Author) , Stenzinger, Albrecht (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: International journal of surgical pathology
Year: 2012, Volume: 21, Issue: 1, Pages: 76-81
ISSN:1940-2465
DOI:10.1177/1066896912448424
Online Access:Verlag, Volltext: http://dx.doi.org/10.1177/1066896912448424
Verlag, Volltext: https://doi.org/10.1177/1066896912448424
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Author Notes:Olcay Cem Bulut, Gerhard Dyckhoff, Wolf Splettstoesser, Johannes Nemeth, Frederick Klauschen, Roland Penzel, Peter K. Plinkert, Christian Simon, Wilko Weichert, and Albrecht Stenzinger
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Summary:This article reports on a 62-year-old man, who presented with cervical mass and rather nonspecific symptoms. The medical history and clinical workup initially favored a malignant disease such as a carcinoma of unknown primary as the underlying cause. Eventually, the patient was diagnosed with a granulomatous lymphadenitis caused by Francisella tularensis subsp holarctica. Tularemia is a rare disease in Western Europe and can present in multiple ways encompassing almost asymptomatic infections and fatal disease. A rapid diagnosis is often hampered by nonspecific symptoms and the generally low prevalence and incidence of this disease in endemic countries. This case report also provides a comprehensive review of the literature on cervical tularemia and discusses the differential diagnoses.
Item Description:Gesehen am 20.06.2018
First published June 6, 2012
Physical Description:Online Resource
ISSN:1940-2465
DOI:10.1177/1066896912448424