Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts
Particle irradiation was established at the University of Heidelberg 2 years ago. To date, more than 400 patients have been treated including patients with primary brain tumors. In malignant glioma (WHO IV) patients, two clinical trials have been set up-one investigating the benefit of a carbon ion...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2012
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| In: |
Radiation oncology
Year: 2012, Volume: 7 |
| ISSN: | 1748-717X |
| DOI: | 10.1186/1748-717X-7-41 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/1748-717X-7-41 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/1748-717X-7-41 
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| Author Notes: | Stefan Rieken, Daniel Habermehl, Thomas Haberer, Oliver Jaekel, Jürgen Debus and Stephanie E. Combs |
| Summary: | Particle irradiation was established at the University of Heidelberg 2 years ago. To date, more than 400 patients have been treated including patients with primary brain tumors. In malignant glioma (WHO IV) patients, two clinical trials have been set up-one investigating the benefit of a carbon ion (18 GyE) vs. a proton boost (10 GyE) in addition to photon radiotherapy (50 Gy), the other one investigating reirradiation with escalating total dose schedules starting at 30 GyE. In atypical meningioma patients (WHO °II), a carbon ion boost of 18 GyE is applied to macroscopic tumor residues following previous photon irradiation with 50 Gy. |
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| Item Description: | Published: 21 March 2012 Gesehen am 22.06.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1748-717X |
| DOI: | 10.1186/1748-717X-7-41 |