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Frequent AKT1E17K mutations in skull base meningiomas are associated with mTOR and ERK1/2 activation and reduced time to tumor recurrence

AbstractBackground. Skull base meningiomas are considered to be difficult for surgical treatment. We wondered whether genetic alterations recently identified

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Bibliographic Details
Main Authors: Yesilöz, Ümmügülsüm (Author) , Kirches, Elmar (Author) , Hartmann, Christian (Author) , Scholz, Johannes (Author) , Kropf, Siegfried (Author) , Sahm, Felix (Author) , Nakamura, Makoto (Author) , Mawrin, Christian (Author)
Format: Article (Journal)
Language:English
Published: 2017
In: Neuro-Oncology
Year: 2017, Volume: 19, Issue: 8, Pages: 1088-1096
ISSN:1523-5866
DOI:10.1093/neuonc/nox018
Online Access:Verlag, Volltext: http://dx.doi.org/10.1093/neuonc/nox018
Verlag, Volltext: https://academic.oup.com/neuro-oncology/article/19/8/1088/3800501
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Author Notes:Ümmügülsüm Yesilöz, Elmar Kirches, Christian Hartmann, Johannes Scholz, Siegfried Kropf, Felix Sahm, Makoto Nakamura, and Christian Mawrin
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Summary:AbstractBackground. Skull base meningiomas are considered to be difficult for surgical treatment. We wondered whether genetic alterations recently identified
Item Description:Published: 06 May 2017
Gesehen am 27.06.2018
Im Titel ist "E17K" hochgestellt
Physical Description:Online Resource
ISSN:1523-5866
DOI:10.1093/neuonc/nox018

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