Poly(aryleneethynylene) tongue that identifies nonsteroidal anti-inflammatory drugs in water: a test case for combating counterfeit drugs
We report a sensor array composed of a highly fluorescent positively charged poly(para-phenyleneethynylene) P1 and its complex C with a negatively charged pyridine-containing poly(para-aryleneethynylene) P2 (quencher) at pH 10 and pH 13; a sensor field composed of four elements, P1 (pH 10), P1 (pH 13)...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
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| In: |
ACS applied materials & interfaces
Year: 2016, Volume: 9, Issue: 1, Pages: 790-797 |
| ISSN: | 1944-8252 |
| DOI: | 10.1021/acsami.6b11690 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1021/acsami.6b11690 Verlag, Volltext: http://pubs.acs.org/doi/10.1021/acsami.6b11690 
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| Author Notes: | Jinsong Han, Benhua Wang, Markus Bender, Soh Kushida, Kai Seehafer, and Uwe H. F. Bunz |
| Summary: | We report a sensor array composed of a highly fluorescent positively charged poly(para-phenyleneethynylene) P1 and its complex C with a negatively charged pyridine-containing poly(para-aryleneethynylene) P2 (quencher) at pH 10 and pH 13; a sensor field composed of four elements, P1 (pH 10), P1 (pH 13), C (pH 10), and C (pH 13), results. The elements of this small sensor field experience either fluorescence turn on or fluorescence quenching upon exposure toward nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, diclofenac, or naproxen. The combined responses of the sensor field are analyzed by linear discriminant analysis (LDA). All of the NSAIDs were identified and discriminated, and the sensing mechanism, hydrophobic versus electrostatic, was discussed. |
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| Item Description: | Published December 16, 2016 Gesehen am 05.07.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1944-8252 |
| DOI: | 10.1021/acsami.6b11690 |