A checkpoint to pain
The checkpoint pathway consisting of programmed death ligand 1 (PD-L1) and its receptor, PD-1, modulates immune function in cancer and infection, but unexpectedly, it also silences pain signals in nerves.
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
27 June 2017
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| In: |
Nature neuroscience
Year: 2017, Volume: 20, Issue: 7, Pages: 897-899 |
| ISSN: | 1546-1726 |
| DOI: | 10.1038/nn.4586 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1038/nn.4586 Verlag, Volltext: https://www.nature.com/articles/nn.4586 |
| Author Notes: | Michael Hirth, Jagadeesh Gandla & Rohini Kuner |
| Summary: | The checkpoint pathway consisting of programmed death ligand 1 (PD-L1) and its receptor, PD-1, modulates immune function in cancer and infection, but unexpectedly, it also silences pain signals in nerves. |
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| Item Description: | Gesehen am 12.07.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1546-1726 |
| DOI: | 10.1038/nn.4586 |