A checkpoint to pain

The checkpoint pathway consisting of programmed death ligand 1 (PD-L1) and its receptor, PD-1, modulates immune function in cancer and infection, but unexpectedly, it also silences pain signals in nerves.

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Bibliographic Details
Main Authors: Hirth, Michael (Author) , Gandla, Jagadeesh (Author) , Kuner, Rohini (Author)
Format: Article (Journal)
Language:English
Published: 27 June 2017
In: Nature neuroscience
Year: 2017, Volume: 20, Issue: 7, Pages: 897-899
ISSN:1546-1726
DOI:10.1038/nn.4586
Online Access:Verlag, Volltext: http://dx.doi.org/10.1038/nn.4586
Verlag, Volltext: https://www.nature.com/articles/nn.4586
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Author Notes:Michael Hirth, Jagadeesh Gandla & Rohini Kuner
Description
Summary:The checkpoint pathway consisting of programmed death ligand 1 (PD-L1) and its receptor, PD-1, modulates immune function in cancer and infection, but unexpectedly, it also silences pain signals in nerves.
Item Description:Gesehen am 12.07.2018
Physical Description:Online Resource
ISSN:1546-1726
DOI:10.1038/nn.4586